# RTDE interface cannot initialize. Make sure that Ethernet/IP adapter and PROFINET are disabled

**URL:** <https://forum.universal-robots.com/t/rtde-interface-cannot-initialize-make-sure-that-ethernet-ip-adapter-and-profinet-are-disabled/15717>\
**Category:** Technical Questions\
**Created:** [August 2, 2021, 10:40am UTC](https://forum.universal-robots.com/t/rtde-interface-cannot-initialize-make-sure-that-ethernet-ip-adapter-and-profinet-are-disabled/15717 "2021-08-02T10:40:01Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![anon41588089](https://avatars.discourse-cdn.com/v4/letter/a/779978/32.png) [@anon41588089](https://forum.universal-robots.com/u/anon41588089)\
**Post date:** [August 2, 2021, 10:40am UTC](https://forum.universal-robots.com/t/rtde-interface-cannot-initialize-make-sure-that-ethernet-ip-adapter-and-profinet-are-disabled/15717/1 "2021-08-02T10:40:01Z")

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Hi,

I have recently upgraded form UR10 to UR16e, connected to S7-1200 via PROFINET. When I try to run the program on robot with UR16e, I get the error message in the title. With UR10, this was not an issue, was able to easily write/read registers and control the program flow from the PLC. With UR16e, only when I disable the PROFINET, program runs. However I need to use Profinet interface to collect signals from the PLC. Is there any way?

Thanks in advance!

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**Author:** ![pho](https://sea2.discourse-cdn.com/flex020/user_avatar/forum.universal-robots.com/pho/32/2275_2.png) [@pho](https://forum.universal-robots.com/u/pho)\
**Post date:** [September 21, 2021, 4:16pm UTC](https://forum.universal-robots.com/t/rtde-interface-cannot-initialize-make-sure-that-ethernet-ip-adapter-and-profinet-are-disabled/15717/2 "2021-09-21T16:16:12Z")

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Very likely you need to be in remote control mode.